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We combine numerous test methods from cell and molecular biology as well as biochemistry, thus allowing us to make detailed claims about the effect of ingredients and formulations. Clients benefit from Phenion´s long experience and top-level expertise, particularly in the areas of skin irritation and in vitro efficacy measurements.
Overview of the diverse combinable in vitro end points, in vitro methods and test designs:

In Vitro Cell and Skin Cultures
Areas of Expertise Skin and eye irritation Cell vitality Skin calming Skin protection Collagen synthesis Melanin synthesis Apoptosis Cell proliferation Protein expression UV protection Penetration ...	Methods and Techniques Cell and molecular biology Histology Immunofluorescence Skin thickness Image analysis ELISA FACS Cytotoxicity and hemolysis (DIN ISO 10993) Lipid synthesis Franz chamber (OECD 428) PCR ...	Tools and Studies Primary cells and cell lines Reconstituted skin Phenion® Full Thickness Skin Model Explants / biopsies of different species HET-CAM ...

In the following you find a detailed description of selected in vitro studies like Soothing the Skin, HET-CAM and Immunohistology.