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Video Tutorials

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6/16/17

Phenion FT Skin Models tissue culture upon arrival

This video tutorial guides you through the first working steps after the skin models have arrived in your lab.

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Protocols

Preview image of Phenion FT Skin Model Instructions for use

Protocol Phenion FT Skin Model Instructions for use

Protocol Phenion FT Skin Model Instructions for use

Preview image of skin model rna isolation instructions pdf

Protocol Phenion FT Skin Model RNA isolation I

Protocol Phenion FT Skin Model RNA isolation I

Preview image of Phenion protocol skin model rna isolation

Protocol Phenion FT Skin Model RNA isolation II

Protocol Phenion FT Skin Model RNA isolation II

Preview image of instruction for phenion skin model separation of epidermis from dermis

Protocol Phenion FT Skin Model Separation of Epidermis from Dermis

Protocol Phenion FT Skin Model Separation of Epidermis from Dermis

Preview image of Phenion feeder cells supported keratinocyte culture for download.

Protocol Phenion Feeder Cell Supported Keratinocyte Culture

Protocol Phenion Feeder Cell Supported Keratinocyte Culture

Preview image for pdf for download with protocol on model histology paraffin sections

Protocol Phenion FT Skin Model Histology - Paraffin sections

Protocol Phenion FT Skin Model Histology - Paraffin sections

Preview image of phenion Phenion skin model histology immunofluorescent labelling

Protocol Phenion FT Skin Model Histology - Immunofluorescent labelling

Protocol Phenion FT Skin Model Histology - Immunofluorescent labelling

Preview image of download Phenion skin model histology frozen section protocol

Protocol Phenion FT Skin Model Histology - Frozen sections

Protocol Phenion FT Skin Model Histology - Frozen sections

References & Further Reading

  • Skin Model Publications
  • Genotox Publications
  • OS-REp Publications
  • Hemicornea Publications
  • Other Publications
Mewes et al., 2017
Reconstructed 3D Tissues for Efficacy and Safety Testing of Cosmetic Ingredients
Dieckmann et al., 2016
A three-dimensional skin equivalent reflecting some aspects of in vivo aged skin.
Alili et al., 2014
A drug-induced accelerated senescence (DIAS) is a possibility to study aging in time lapse.
Ackermann et al., 2010
The Phenion full-thickness skin model for percutaneous absorption testing.
Zöller et al., 2008
Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model.
Mewes et al., 2007
Elastin expression in a newly developed full-thickness skin equivalent.
Lee et al., 2006
An in vivo analysis of MMC-induced DNA damage and its repair.
Pfuhler et al., 2014
The Cosmetics Europe strategy for animal-free genotoxicity testing: project status up-date.
Hewitt et al., 2013
Use of human in vitro skin modesl for accurate and ethical risk assessment: metabolic considerations.
Alépée et al., 2016 Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay.

Barroso et al., 2015
Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.
Zorn-Kruppa et al., 2014
Determining the depthDetermining the Depth of Injury in Bioengineered Tissue Models of Cornea and Conjunctiva for the Prediction of All Three Ocular GHS Categories.
Engelke et al., 2013
A human hemi-cornea model for eye irritation testing: quality control of production, reliability and predictive capacity.

Russell, William M.S. / Burch, Rex L. (1959): The Principles of Humane Experimental Technique. London: Methuen